What They Are:

• Both Semaglutide/Tirzepatide are Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAs) that Mimic the Action of the Hormone GLP-1.

• GLP-1 Slows Gastric Emptying, increases Insulin Secretion, and Decreases Glucagon Release.

How Do They Work:

Both Help with Weight Loss by:

• Slowing Gastric Emptying, which can help you feel full for longer 

• Reducing glucagon production, which decreases the amount of sugar made by your liver 

• Increasing insulin secretion, which helps lower blood sugar levels 

• Acting on areas of the brain that regulate hunger, fullness, and cravings 

What are the Differences:

• Tirzepatide targets both the GLP-1 and Glucose-Dependent insulinotropic polypeptide (GIP) Receptors, while Semaglutide Primarily Targets the GLP-1 Receptor.

Brand Names:

• Tirzepatide is Sold under the Brand Name Zepbound, and Semaglutide is Sold under the Brand Name Wegovy. 

Side Effects:

Common Side Effects of Both include -Nausea, Vomiting, and Gastrointestinal issues. 

What Happens When You Switch from Semaglutide to Tirzepatide?

In Research involving people with type 2 diabetes who switched from Semaglutide to Tirzepatide, participants stopped Semaglutide 3 to 10 days before starting Tirzepatide. After the Switch, some people experienced gastrointestinal side effects like Nausea, Constipation, and Diarrhea.

For Optimal Results, You Should Use Semaglutide [OR] Tirzepatide alongside Proper Nutrition and Exercise!